Overview |
bs-6468R-Cy3 |
kir 6.1 Polyclonal Antibody, Cy3 Conjugated |
WB, IF(IHC-P), IF(IHC-F), IF(ICC) |
Rat |
Human, Mouse, Cow, Pig, Chicken, Rabbit |
Specifications |
Cy3 |
Rabbit |
KLH conjugated synthetic peptide derived from human kir 6.1 |
61-160/424 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
3764 |
Q15842 |
Cell membrane |
KIR6.1; uKATP-1; ATP-sensitive inward rectifier potassium channel 8; Inward rectifier K(+) channel Kir6.1; Potassium channel, inwardly rectifying subfamily J member 8; KCNJ8 |
This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium (By similarity). |
Application Dilution |
WB |
1:300-5000 |
IF(IHC-P) |
1:50-200 |
IF(IHC-F) |
1:50-200 |
IF(ICC) |
1:50-200 |