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MAPK9 Polyclonal Antibody

Applications

  • WB
  • IHC-P
  • IF(ICC)
  • IHC
  • IF

Reactivity

  • Human
  • Mouse
Overview
Catalog # bs-55130R
Product Name MAPK9 Polyclonal Antibody
Applications WB, IHC-P, IF(ICC), IHC, IF
Reactivity Human, Mouse
Specifications
Conjugation Unconjugated
Host Rabbit
Source Recombinant fusion protein containing a sequence corresponding to amino acids 1-424 of human MAPK9 (NP_002743.3).
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 5601
Swiss Prot P45984
Subcellular location Cytoplasm, Nucleus
Synonyms MAPK9;JNK-55;JNK2;JNK2A;JNK2ALPHA;JNK2B;JNK2BETA;PRKM9;SAPK;SAPK1a;p54a;p54aSAPK
Background The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.
Application Dilution
WB 1:300-5000
IHC-P 1:200-400
IF(ICC) 1:50-200
IHC
IF