IRF3 Polyclonal Antibody
Applications
Reactivity
Overview | |
Catalog # | bs-55112R |
Product Name | IRF3 Polyclonal Antibody |
Applications | WB, IHC-P, IHC |
Reactivity | Human, Mouse, Rat |
Specifications | |
Conjugation | Unconjugated |
Host | Rabbit |
Source | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human IRF3 (NP_001184051.1). |
Clonality | Polyclonal |
Isotype | IgG |
Concentration | 1ug/ul |
Purification | Purified by Protein A. |
Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Storage Condition | Store at -20°C for 12 months. |
Target | |
Gene ID | 3661 |
Swiss Prot | Q14653 |
Subcellular location | Cytoplasm, Nucleus |
Synonyms | IIAE7;IRF3 |
Background | This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
Application Dilution | |
WB | 1:300-5000 |
IHC-P | 1:200-400 |
IHC |