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Cytokeratin-8 Polyclonal Antibody

Applications

  • WB
  • IHC-P
  • IF(ICC)
  • IHC
  • IF

Reactivity

  • Human
  • Mouse
Overview
Catalog # bs-55051R
Product Name Cytokeratin-8 Polyclonal Antibody
Applications WB, IHC-P, IF(ICC), IHC, IF
Reactivity Human, Mouse
Specifications
Conjugation Unconjugated
Host Rabbit
Source Recombinant fusion protein containing a sequence corresponding to amino acids 1-483 of human Cytokeratin-8 (NP_002264.1).
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 3856
Swiss Prot P05787
Subcellular location Cytoplasm, Nucleus
Synonyms KRT8;CARD2;CK-8;CK8;CYK8;K2C8;K8;KO;keratin 8
Background This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.
Application Dilution
WB 1:300-5000
IHC-P 1:200-400
IF(ICC) 1:50-200
IHC
IF