Overview |
bs-5376R-PE-Cy3 |
G3BP1(Ser232) Polyclonal Antibody, PE-Cy3 Conjugated |
WB |
Human |
Cow, Pig, Rabbit |
Specifications |
PE-Cy3 |
Rabbit |
KLH conjugated synthetic phosphopeptide derived from human G3BP1 around the phosphorylation site of Ser232 |
Ser232 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
10146 |
Q13283 |
Cytoplasm, Nucleus, Cell membrane |
G3BP; HDH-VIII; Ras GTPase-activating protein-binding protein 1; G3BP-1; ATP-dependent DNA helicase VIII; hDH VIII; GAP SH3 domain-binding protein 1; G3BP1 |
May be a regulated effector of stress granule assembly. Phosphorylation-dependent sequence-specific endoribonuclease in vitro. Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR. ATP- and magnesium-dependent helicase. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA. |
Application Dilution |
WB |
1:300-5000 |