CBX2 Polyclonal Antibody

Overview
Catalog #	bs-53083R
Product Name	CBX2 Polyclonal Antibody
Applications	ELISA
Reactivity	Mouse
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	Polyclonal antibody raised in rabbit against mouse CBX2 (chromobox homolog 2) using two KLH-conjugated synthetic peptides containing a sequence from the central region of the protein
Clonality	Polyclonal
Isotype	Not Determined
Concentration	Not Determined
Purification	Whole antiserum from rabbit containing 0.05% azide
Storage Buffer	Serum with 0.05% sodium azide.
Storage Condition	Store at -20°C for 12 months.
Target
Gene ID	84733
Swiss Prot	Q14781
Synonyms	Chromobox protein homolog 2, CBX2
Background	Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Involved in sexual development, acting as activator of NR5A1 expression.
Application Dilution
ELISA	1:500-1000