Overview |
bs-4819R-Cy7 |
CD45 Polyclonal Antibody, Cy7 Conjugated |
WB, IF(IHC-P), IF(IHC-F) |
Human, Mouse, Rat |
Specifications |
Cy7 |
Rabbit |
KLH conjugated synthetic peptide derived from rat CD45 |
501-600/1273 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
24699 |
P04157 |
Cell membrane |
Lca; RT7; CD45; L-CA; T200; Receptor-type tyrosine-protein phosphatase C; Leukocyte common antigen; Ptprc |
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN (By similarity). Dephosphorylates LYN, and thereby modulates LYN activity (By similarity). |
Application Dilution |
WB |
1:300-5000 |
IF(IHC-P) |
1:50-200 |
IF(IHC-F) |
1:50-200 |