| Overview |
| bs-4563R-PE |
| Bcl-2 Polyclonal Antibody, PE Conjugated |
| WB, FCM |
| Human, Mouse, Rat, Pig, Sheep, Rabbit |
| Dog, Cow, Horse |
| Specifications |
| PE |
| Rabbit |
| KLH conjugated synthetic peptide derived from human Bcl-2 |
| 161-239/239 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 596 |
| P10415 |
| Cytoplasm, Nucleus, Cell membrane |
| Bcl-2; PPP1R5; Apoptosis regulator Bcl-2; BCL2 |
| Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). |
| Application Dilution |
| WB |
1:300-5000 |
| FCM |
1:20-100 |
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