Overview |
bs-3737R-PE-Cy7 |
PPAR Gamma (ser112) Polyclonal Antibody, PE-Cy7 Conjugated |
WB, FCM |
Human, Mouse, Rat, Dog |
Pig, Rabbit, Guinea Pig |
Specifications |
PE-Cy7 |
Rabbit |
KLH conjugated synthetic phosphopeptide derived from human PPAR Gamma around the phosphorylation site of ser112 |
ser112 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
5468 |
P37231 |
Cytoplasm, Nucleus |
GLM1; CIMT1; NR1C3; PPARG1; PPARG2; PPARgamma; Peroxisome proliferator-activated receptor gamma; PPAR-gamma; Nuclear receptor subfamily 1 group C member 3; PPARG |
Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B-mediated proinflammatory responses. |
Application Dilution |
WB |
1:300-5000 |
FCM |
1:20-100 |