| Overview |
| bs-3429R-PE-Cy5 |
| STAT3 (Ser727) Polyclonal Antibody, PE-Cy5 Conjugated |
| WB, FCM |
| Human, Rat, Rabbit |
| Mouse, Dog, Cow, Sheep, Pig, Chicken, Guinea Pig |
| Specifications |
| PE-Cy5 |
| Rabbit |
| KLH conjugated synthetic phosphopeptide derived from human STAT3 around the phosphorylation site of Ser727 |
| Ser727 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 6774 |
| P40763 |
| Cytoplasm, Nucleus |
| APRF; HIES; ADMIO; Signal transducer and activator of transcription 3; Acute-phase response factor; STAT3 |
| Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA. Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity. Plays an important role in host defense in methicillin-resistant S.aureus lung infection by regulating the expression of the antimicrobial lectin REG3G (By similarity). |
| Application Dilution |
| WB |
1:300-5000 |
| FCM |
1:20-100 |
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