Overview |
bs-3191R-Cy3 |
IKB beta (Ser23) Polyclonal Antibody, Cy3 Conjugated |
WB, IF(IHC-P), IF(IHC-F), IF(ICC) |
Human |
Mouse, Rat, Cow, Pig, Horse, Rabbit |
Specifications |
Cy3 |
Rabbit |
KLH conjugated synthetic phosphopeptide derived from human NFKBIB around the phosphorylation site of Ser23 |
Ser23 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
4793 |
Cytoplasm, Nucleus |
IKB beta Ser23; IKB beta S23; p-IKB beta Ser23; p-IKB beta S23; NFKBIBSer23; NFKBIBphospho S23; IkB-betaSer22; IkB beta; NF-kappa-B inhibitor beta; IKB beta; NF-kappa-BIB; TRIP-9; I-kappa-B-beta; IkappaBbeta; IkB-beta; IkB-B; Thyroid receptor-interacting protein 9; TR-interacting protein 9; NFKBIB; IKBB. |
The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jul 2011]. |
Application Dilution |
WB |
1:300-5000 |
IF(IHC-P) |
1:50-200 |
IF(IHC-F) |
1:50-200 |
IF(ICC) |
1:50-200 |