| Overview |
| bs-3186R-BF405 |
| Histone H3 (Ser11) Polyclonal Antibody, AbBy Fluor® 405 Conjugated |
| FCM, IF(IHC-P), IF(IHC-F), IF(ICC) |
| Human, Mouse, Rat |
| Cow, Pig, Rabbit, Drosophila |
| Specifications |
| AbBy Fluor® 405 |
| Rabbit |
| KLH conjugated synthetic phosphopeptide derived from human Histone H3 around the phosphorylation site of Ser11 |
| Ser11 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 8290 |
| Q16695 |
| H3t; H3.4; H3/g; H3FT; Histone H3.1t; H3/t; HIST3H3 |
| Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
| Application Dilution |
| FCM |
1:20-100 |
| IF(IHC-P) |
1:50-200 |
| IF(IHC-F) |
1:50-200 |
| IF(ICC) |
1:50-200 |
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