Overview |
bs-2774R-Cy7 |
Prox1 Polyclonal Antibody, Cy7 Conjugated |
WB, FCM, IF(IHC-P) |
Human, Mouse, Rat |
Dog, Cow, Pig, Horse, Rabbit |
Specifications |
Cy7 |
Rabbit |
KLH conjugated synthetic peptide derived from human Prox-1 |
151-250/737 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
5629 |
Q92786 |
Nucleus |
Prospero homeobox protein 1; Homeobox prospero-like protein PROX1; PROX-1; PROX1 |
Transcription factor involved in developmental processes such as cell fate determination, gene transcriptional regulation and progenitor cell regulation in a number of organs. Plays a critical role in embryonic development and functions as a key regulatory protein in neurogenesis and the development of the heart, eye lens, liver, pancreas and the lymphatic system. Involved in the regulation of the circadian rhythm. Represses: transcription of the retinoid-related orphan receptor RORG, transcriptional activator activity of RORA and RORG and the expression of RORA/G-target genes including core clock components: ARNTL/BMAL1, NPAS2 and CRY1 and metabolic genes: AVPR1A and ELOVL3. |
Application Dilution |
WB |
1:300-5000 |
FCM |
1:20-100 |
IF(IHC-P) |
1:50-200 |