CENPA Polyclonal Antibody
Applications
Reactivity
Overview | |
Catalog # | bs-2753R |
Product Name | CENPA Polyclonal Antibody |
Applications | WB, ELISA, IHC-P |
Reactivity | Human, Mouse, Rat |
Specifications | |
Conjugation | Unconjugated |
Host | Rabbit |
Source | KLH conjugated synthetic peptide derived from human CENPA |
Immunogen Range | 65-140/140 |
Clonality | Polyclonal |
Isotype | IgG |
Concentration | 1ug/ul |
Purification | Purified by Protein A. |
Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Storage Condition | Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Target | |
Gene ID | 1058 |
Swiss Prot | P49450 |
Subcellular location | Nucleus |
Synonyms | CenH3; CENP-A; Histone H3-like centromeric protein A; Centromere autoantigen A; Centromere protein A; CENPA |
Background | Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division. The CENPA-H4 heterotetramer can bind DNA by itself (in vitro). |
Application Dilution | |
WB | 1:300-5000 |
ELISA | 1:500-1000 |
IHC-P | 1:100-500 |