ICOS-L/B7-H2/CD275 Polyclonal Antibody

Overview
Catalog #	bs-2471R
Product Name	ICOS-L/B7-H2/CD275 Polyclonal Antibody
Applications	WB, ELISA, FCM
Reactivity	Human, Mouse
Predicted Reactivity	Rat
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	KLH conjugated synthetic peptide derived from Rat ICOS-L
Immunogen Range	19-120/302
Clonality	Polyclonal
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition	Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID	23308
Swiss Prot	O75144
Subcellular location	Cell membrane
Synonyms	B7H2; GL50; B7-H2; B7RP1; CD275; ICOSL; LICOS; B7RP-1; ICOS-L; ICOS ligand; B7 homolog 2; B7-like protein Gl50; B7-related protein 1; ICOSLG; KIAA0653
Background	Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function (By similarity).
Application Dilution
WB	1:300-5000
ELISA	1:500-1000
FCM	1:20-100