KLRC Family Polyclonal Antibody

$Image kindly submitted by Shoko Hagen at Oregon Health and Science University.\\n\\nRhesus Macaques PBMCs were stained with 5uL per tube of Rabbit Anti-NKG2C Polyclonal Antibody, FITC Conjugated (bs-2416R-FITC)$

Image kindly submitted by Shoko Hagen at Oregon Health and Science University.\\n\\nRhesus Macaques PBMCs were stained with 5uL per tube of Rabbit Anti-NKG2C Polyclonal Antibody, FITC Conjugated (bs-2416R-FITC)

Applications

ELISA
FCM
IHC-P
IHC-F
IF(IHC-P)
IF(IHC-F)
IF(ICC)

Reactivity

Others
Monkey

Predicted Reactivity

Human

Overview
Catalog #	bs-2416R
Product Name	KLRC Family Polyclonal Antibody
Applications	ELISA, FCM, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC)
Reactivity	Others, Monkey
Predicted Reactivity	Human
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	KLH conjugated synthetic peptide derived from human NKG2C
Immunogen Range	51-150/231
Clonality	Polyclonal
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition	Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID	3822
Swiss Prot	P26717
Subcellular location	Cell membrane
Synonyms	KLRC1; NKG2-A/NKG2-B type II integral membrane protein; CD159a; NKG2-A/B-activating NK receptor; NK cell receptor A; NKG2A; NKG2B; KLRC2; NKG2-C type II integral membrane protein; CD159c; NK cell receptor C; NKG2-C-activating NK receptor; NKG2C; KLRC3; NKG2-E type II integral membrane protein; NK cell receptor E; NKG2-E-activating NK receptor; NKG2E; KLRC4; NKG2-F type II integral membrane protein; NK cell receptor F; NKG2-F-activating NK receptor; NKG2F.
Background	Natural killer (NK) cells are lymphocytes that can mediate the lysis of certain tumor cells and virus infected cells without being previously activated. They can also regulate specific humoral and cell mediated immunity. NK cells preferentially express several calcium dependent (C type) lectins, which have been implicated in the regulation of NK cell function. The group, designated KLRC (NKG2) are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C type lectin domain. The KLRC (NKG2) gene family is located within the NK complex, a region that contains several C type lectin genes preferentially expressed on NK cells.
Application Dilution
ELISA	1:500-1000
FCM	1:20-100
IHC-P	1:200-400
IHC-F	1:100-500
IF(IHC-P)	1:50-200
IF(IHC-F)	1:50-200
IF(ICC)	1:50-200