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CD80 Polyclonal Antibody, Biotin Conjugated

Applications

  • WB
  • ELISA

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bs-23296R-Biotin
Product Name CD80 Polyclonal Antibody, Biotin Conjugated
Applications WB, ELISA
Reactivity Human, Mouse, Rat
Specifications
Conjugation Biotin
Host Rabbit
Source KLH conjugated synthetic peptide derived from mouse CD80
Immunogen Range 1-100/306
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 12519
Swiss Prot Q00609
Subcellular location Cell membrane
Synonyms T-lymphocyte activation antigen CD80; Cd80; Activation B7-1 antigen; B7;
Background CD80 is a member of the Ig superfamily and serves as the ligand for two T cell molecules, CD28 and CTLA4. Interactions between CD28 and CD80 on activated B cells result in enhanced T cell activation. CD80 is rapidly induced on the surface of in vitro activated B cells, Epstein Barr Virus (EBV) transformed B cell lines, Burkitts lymphoma cell lines, freshly isolated follicular B lymphoma cells, T cells, and monocytes. It is also expressed at high levels in dendritic cells. It reacts weakly with a small proportion of non activated normal B cells and with HTLV1 infected T cells. CD80 does not react with peripheral monocytes, resting and activated normal T cells, T cell lines and T cell clones, nor with myelomonocytic cell lines.
Application Dilution
WB 1:300-5000
ELISA 1:500-1000