CD80 Polyclonal Antibody
Applications
Reactivity
Overview | |
Catalog # | bs-23296R |
Product Name | CD80 Polyclonal Antibody |
Applications | WB, ELISA |
Reactivity | Human, Mouse, Rat |
Specifications | |
Conjugation | Unconjugated |
Host | Rabbit |
Source | KLH conjugated synthetic peptide derived from mouse CD80 |
Immunogen Range | 1-100/306 |
Clonality | Polyclonal |
Isotype | IgG |
Concentration | 1ug/ul |
Purification | Purified by Protein A. |
Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Storage Condition | Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Target | |
Gene ID | 12519 |
Swiss Prot | Q00609 |
Subcellular location | Cell membrane |
Synonyms | T-lymphocyte activation antigen CD80; Cd80; Activation B7-1 antigen; B7; |
Background | CD80 is a member of the Ig superfamily and serves as the ligand for two T cell molecules, CD28 and CTLA4. Interactions between CD28 and CD80 on activated B cells result in enhanced T cell activation. CD80 is rapidly induced on the surface of in vitro activated B cells, Epstein Barr Virus (EBV) transformed B cell lines, Burkitts lymphoma cell lines, freshly isolated follicular B lymphoma cells, T cells, and monocytes. It is also expressed at high levels in dendritic cells. It reacts weakly with a small proportion of non activated normal B cells and with HTLV1 infected T cells. CD80 does not react with peripheral monocytes, resting and activated normal T cells, T cell lines and T cell clones, nor with myelomonocytic cell lines. |
Application Dilution | |
WB | 1:300-5000 |
ELISA | 1:500-1000 |