Overview |
bs-23296R-Biotin |
CD80 Polyclonal Antibody, Biotin Conjugated |
WB, ELISA |
Human, Mouse, Rat |
Specifications |
Biotin |
Rabbit |
KLH conjugated synthetic peptide derived from mouse CD80 |
1-100/306 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C for 12 months. |
Target |
12519 |
Q00609 |
Cell membrane |
T-lymphocyte activation antigen CD80; Cd80; Activation B7-1 antigen;
B7; |
CD80 is a member of the Ig superfamily and serves as the ligand for two T cell molecules, CD28 and CTLA4. Interactions between CD28 and CD80 on activated B cells result in enhanced T cell activation. CD80 is rapidly induced on the surface of in vitro activated B cells, Epstein Barr Virus (EBV) transformed B cell lines, Burkitts lymphoma cell lines, freshly isolated follicular B lymphoma cells, T cells, and monocytes. It is also expressed at high levels in dendritic cells. It reacts weakly with a small proportion of non activated normal B cells and with HTLV1 infected T cells. CD80 does not react with peripheral monocytes, resting and activated normal T cells, T cell lines and T cell clones, nor with myelomonocytic cell lines. |
Application Dilution |
WB |
1:300-5000 |
ELISA |
1:500-1000 |