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IL-23R Polyclonal Antibody, FITC Conjugated

Applications

  • WB

Reactivity

  • Human

Predicted Reactivity

  • Rat
Overview
Catalog # bs-22608R-FITC
Product Name IL-23R Polyclonal Antibody, FITC Conjugated
Applications WB
Reactivity Human
Predicted Reactivity Rat
Specifications
Conjugation FITC
Host Rabbit
Source KLH conjugated synthetic peptide derived from human IL-23R
Immunogen Range 231-330/629
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 149233
Swiss Prot Q5VWK5
Subcellular location Cell membrane
Synonyms IL23 Receptor; IL-23R; IL23R; interleukin 23 receptor; IL 23R; IL-23 receptor; IL23R_HUMAN; Interleukin-23 receptor.
Background Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis. Subunit : Heterodimer with IL12RB1. In presence of IL23, the heterodimer forms the IL23 receptor. Interacts with JAK2 and in presence of IL23 with STAT3.
Application Dilution
WB 1:300-5000