Overview |
bs-2130R-Biotin |
Ki-67 (Proliferation Marker) Antibody, Biotin Conjugated |
ELISA, IHC-P |
Human, Mouse, Rat |
Specifications |
Biotin |
Rabbit |
KLH conjugated synthetic peptide derived from human Ki67 |
1201-1300/3256 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C for 12 months. |
Target |
4288 |
P46013 |
Nucleus |
KIA; MIB-; MIB-1; PPP1R15; Antigen KI-67; MKI67 |
Proliferation Marker Ki67 antigen is the prototypic cell cycle related nuclear protein, expressed by proliferating cells in all phases of the active cell cycle (G1, S, G2 and M phase). It is absent in resting (G0) cells. Ki67 are useful in establishing the cell growing fraction in neoplasms (immunohistochemically quantified by determining the number of Ki67 positive cells among the total number of resting cells = Ki67 index). In neoplastic tissues the prognostic value is comparable to the tritiated thymidine labelling index. The correlation between low Ki67 index and histologically low grade tumours is strong. Ki67 is routinely used as a neuronal marker of cell cycling and proliferation. |
Application Dilution |
ELISA |
1:500-1000 |
IHC-P |
1:200-400 |