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Heme oxygenase 1 Polyclonal Antibody, Biotin Conjugated

Applications

  • WB
  • ELISA
  • IHC-P
  • IHC-F

Reactivity

  • Human
  • Mouse
  • Rat
  • Pig
  • Chicken

Predicted Reactivity

  • Dog
  • Cow
  • Sheep
  • Horse
  • Rabbit
  • Guinea Pig
Overview
Catalog # bs-2075R-Biotin
Product Name Heme oxygenase 1 Polyclonal Antibody, Biotin Conjugated
Applications WB, ELISA, IHC-P, IHC-F
Reactivity Human, Mouse, Rat, Pig, Chicken
Predicted Reactivity Dog, Cow, Sheep, Horse, Rabbit, Guinea Pig
Specifications
Conjugation Biotin
Host Rabbit
Source KLH conjugated synthetic peptide derived from human Heme Oxygenase 1
Immunogen Range 101-200/288
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 3162
Swiss Prot P09601
Subcellular location Cytoplasm
Synonyms HO-1; HSP32; HMOX1D; bK286B1; HMOX1; HO; HO1
Background Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis.
Application Dilution
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500