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KCNH2 Polyclonal Antibody

Applications

  • ELISA
  • FCM
  • ICC

Reactivity

  • Human
  • Rat

Predicted Reactivity

  • Mouse
  • Dog
  • Pig
  • Horse
  • Rabbit
Overview
Catalog # bs-1815R
Product Name KCNH2 Polyclonal Antibody
Applications ELISA, FCM, ICC
Reactivity Human, Rat
Predicted Reactivity Mouse, Dog, Pig, Horse, Rabbit
Specifications
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic peptide derived from human HERG
Immunogen Range 1001-1159/1159
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID 3757
Swiss Prot Q12809
Subcellular location Cell membrane
Synonyms ERG1; HERG; LQT2; SQT1; ERG-1; H-ERG; HERG1; Kv11.1; Potassium voltage-gated channel subfamily H member 2; Eag homolog; Ether-a-go-go-related gene potassium channel 1; Eag-related protein 1; Ether-a-go-go-related protein 1; hERG-1; Voltage-gated potassium channel subunit Kv11.1; KCNH2; ERG
Background Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr). Isoforms USO have no channel activity by themself, but modulates channel characteristics by forming heterotetramers with other isoforms which are retained intracellularly and undergo ubiquitin-dependent degradation.
Application Dilution
ELISA 1:500-1000
FCM 1:20-100
ICC 1:100-500