Overview |
bs-1722R-HRP |
E2F3 Polyclonal Antibody, HRP Conjugated |
WB, ELISA, IHC-P, IHC-F |
Human, Mouse |
Rat, Dog, Cow, Pig, Horse, Rabbit |
Specifications |
HRP |
Rabbit |
KLH conjugated synthetic peptide derived from human E2F3 |
381-465/465 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
1871 |
O00716 |
Nucleus |
E2F-3; Transcription factor E2F3; E2F3; KIAA0075 |
Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F3 binds specifically to RB1 in a cell-cycle dependent manner. Inhibits adipogenesis, probably through the repression of CEBPA binding to its target gene promoters (By similarity). |
Application Dilution |
WB |
1:300-5000 |
ELISA |
1:500-1000 |
IHC-P |
1:200-400 |
IHC-F |
1:100-500 |