RELN/Reelin Polyclonal Antibody

$Formalin-fixed and paraffin embedded rat hippocampus labeled with Anti-RELN\/REELIN Polyclonal Antibody, Unconjugated (bs-1560R) followed by conjugation to the secondary antibody and DAB staining$

Formalin-fixed and paraffin embedded rat hippocampus labeled with Anti-RELN\/REELIN Polyclonal Antibody, Unconjugated (bs-1560R) followed by conjugation to the secondary antibody and DAB staining

Applications

IHC-P
IF(IHC-P)

Reactivity

Human
Mouse
Rat

Overview
Catalog #	bs-1560r-100ul
Product Name	RELN/Reelin Polyclonal Antibody
Applications	IHC-P, IF(IHC-P)
Reactivity	Human, Mouse, Rat
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	KLH conjugated synthetic peptide derived from human RELN
Immunogen Range	3320-3370/3458
Clonality	Polyclonal
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition	Store at -20°C for 12 months.
Target
Gene ID	5649
Swiss Prot	P78509
Subcellular location	Extracellular, Secreted
Synonyms	RL; ETL7; LIS2; PRO1598; Reelin; RELN
Background	Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation (By similarity).
Application Dilution
IHC-P	1:200-400
IF(IHC-P)	1:50-200