| Overview |
| bs-1544R-BF350 |
| Shh Polyclonal Antibody, AbBy Fluor® 350 Conjugated |
| WB, IF(IHC-P), IF(IHC-F), IF(ICC) |
| Human, Mouse, Rat, Pig |
| Cow, Horse, Chicken, Rabbit |
| Specifications |
| AbBy Fluor® 350 |
| Rabbit |
| KLH conjugated synthetic peptide derived from human Shh |
| 21-120/462 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 6469 |
| Q15465 |
| Secreted, Cell membrane, Extracellular matrix |
| TPT; HHG1; HLP3; HPE3; SMMCI; TPTPS; MCOPCB5; Sonic hedgehog protein; SHH; HHG-1 |
| Intercellular signal essential for a variety of patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites, and the polarizing signal for patterning of the anterior-posterior axis of the developing limb bud. Displays both floor plate- and motor neuron-inducing activity. The threshold concentration of N-product required for motor neuron induction is 5-fold lower than that required for floor plate induction. Activates the transcription of target genes by interacting with its receptor PTCH1 to prevent normal inhibition by PTCH1 on the constitutive signaling activity of SMO (By similarity). |
| Application Dilution |
| WB |
1:300-5000 |
| IF(IHC-P) |
1:50-200 |
| IF(IHC-F) |
1:50-200 |
| IF(ICC) |
1:50-200 |
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