Overview |
bs-1483R-HRP |
RBBP6/P2P-R Polyclonal Antibody, HRP Conjugated |
WB, ELISA, IHC-P, IHC-F |
Mouse, Rat |
Human |
Specifications |
HRP |
Rabbit |
KLH conjugated synthetic peptide derived from human P2PR |
2-150/1792 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
5930 |
Q7Z6E9 |
Cytoplasm, Nucleus |
PACT; MY038; P2P-R; RBQ-1; SNAMA; E3 ubiquitin-protein ligase RBBP6; Proliferation potential-related protein; Protein P2P-R; Retinoblastoma-binding Q protein 1; Retinoblastoma-binding protein 6; p53-associated cellular protein of testis; RBBP6; P2PR; RBQ1 |
E3 ubiquitin-protein ligase which promotes ubiquitination of YBX1, leading to its degradation by the proteasome. May play a role as a scaffold protein to promote the assembly of the p53/TP53-MDM2 complex, resulting in increase of MDM2-mediated ubiquitination and degradation of p53/TP53; may function as negative regulator of p53/TP53, leading to both apoptosis and cell growth. |
Application Dilution |
WB |
1:300-5000 |
ELISA |
1:500-1000 |
IHC-P |
1:200-400 |
IHC-F |
1:100-500 |