Overview |
bs-14654R-APC |
EXD2 Polyclonal Antibody, APC Conjugated |
WB, IF(IHC-P), IF(IHC-F), IF(ICC) |
WB shows isoform 2 |
Human, Mouse, Rat |
Dog, Cow, Sheep, Pig, Horse |
Specifications |
APC |
Rabbit |
KLH conjugated synthetic peptide derived from human EXD2 |
351-621/621 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
55218 |
Q9NVH0 |
Nucleus |
Exonuclease 3'-5' domain-containing protein 2; EXD2; C14orf114; EXDL2 |
Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks. |
Application Dilution |
WB |
1:300-5000 |
IF(IHC-P) |
1:50-200 |
IF(IHC-F) |
1:50-200 |
IF(ICC) |
1:50-200 |