Overview |
bs-1424R-PE-Cy7 |
EPOR Polyclonal Antibody, PE-Cy7 Conjugated |
WB |
Human, Mouse, Rat |
Dog, Cow, Horse |
Specifications |
PE-Cy7 |
Rabbit |
KLH conjugated synthetic peptide derived from human EPOR |
301-450/508 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
2057 |
P19235 |
Secreted, Cell membrane, Extracellular matrix |
EPO-R; Erythropoietin receptor; EPOR |
Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase. Isoform EPOR-T acts as a dominant-negative receptor of EPOR-mediated signaling. |
Application Dilution |
WB |
1:300-5000 |