CLEC12A Polyclonal Antibody, PE-Cy5 Conjugated
Applications
Predicted Reactivity
Overview | |
Catalog # | bs-13628R-PE-Cy5 |
Product Name | CLEC12A Polyclonal Antibody, PE-Cy5 Conjugated |
Applications | WB |
Predicted Reactivity | Human, Mouse, Rat |
Specifications | |
Conjugation | PE-Cy5 |
Host | Rabbit |
Source | KLH conjugated synthetic peptide derived from human CLEC12A |
Immunogen Range | 61-160/265 |
Clonality | Polyclonal |
Isotype | IgG |
Concentration | 1ug/ul |
Purification | Purified by Protein A. |
Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target | |
Subcellular location | Cell membrane |
Synonyms | C-type lectin domain family 12 member A; C-type lectin-like molecule 1; CL12A_HUMAN; CLEC12A; CLL-1; DCAL-2; Dendritic cell-associated lectin 2; MICL; Myeloid inhibitory C-type lectin-like receptor. |
Background | The C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily consists of a variety of proteins that share a common protein fold and have diverse functions, including cell-cell signaling, cell adhesion, glycoprotein turnover and immune responses. CLEC-12A (C-type lectin domain family 12, member A), also known as CLL1, MICL, CLL-1 or DCAL-2, is a 275 amino acid single-pass type II membrane protein that contains one C-type lectin domain and belongs to the CTL/CTLD superfamily. Existing as multiple alternatively spliced isoforms that are expressed in neutrophils, eosinophils, monocytes and dendritic cells, CLEC-12A functions as a cell surface receptor that acts as a negative regulator of granulocyte and monocyte function and, via this activity, modulates signaling cascades. CLEC-12A is highly subject to post-translational glycosylation at its N-terminus and may also exist as a homodimer. |
Application Dilution | |
WB | 1:300-5000 |