LYVE-1 Polyclonal Antibody

Formalin-fixed and paraffin embedded human breast cancer tissue labeled with Anti-LYVE-1 Polyclonal Antibody, Unconjugated (bs-1311R) followed by conjugation to the secondary antibody and DAB staining

$Lane 1: Mouse Liver tissue lysates; Lane 2: Mouse Spleen tissue lysates; Lane 3: Human Huvec cell lysates; Lane 4: Human K562 cell lysates probed with LYVE-1 Polyclonal Antibody, Unconjugated (bs-1311R) at 1:1000 dilution and 4\u00b0C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.$

Lane 1: Mouse Liver tissue lysates; Lane 2: Mouse Spleen tissue lysates; Lane 3: Human Huvec cell lysates; Lane 4: Human K562 cell lysates probed with LYVE-1 Polyclonal Antibody, Unconjugated (bs-1311R) at 1:1000 dilution and 4\u00b0C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.

Applications

WB
ELISA
IHC-P

Reactivity

Human
Mouse

Predicted Reactivity

Overview
Catalog #	bs-1311R
Product Name	LYVE-1 Polyclonal Antibody
Applications	WB, ELISA, IHC-P
Reactivity	Human, Mouse
Predicted Reactivity	Rat
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	KLH conjugated synthetic peptide derived from mouse LYVE-1
Immunogen Range	231-318/318
Clonality	Polyclonal
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition	Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID	114332
Swiss Prot	Q8BHC0
Subcellular location	Cytoplasm, Cell membrane, Extracellular matrix
Synonyms	Xlkd1; Lyve-1; Crsbp-1; 1212G8Rik; Lymphatic vessel endothelial hyaluronic acid receptor 1; Cell surface retention sequence-binding protein 1; Extracellular link domain-containing protein 1; Lyve1; Crsbp1
Background	Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as a hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes.
Application Dilution
WB	1:300-5000
ELISA	1:500-1000
IHC-P	1:200-400