Overview |
bs-12720R-APC |
PLEKHA1 Polyclonal Antibody, APC Conjugated |
WB, IF(IHC-P), IF(IHC-F), IF(ICC) |
Mouse |
Human, Rat, Cow, Sheep, Pig, Horse |
Specifications |
APC |
Rabbit |
KLH conjugated synthetic peptide derived from human PLEKHA1 |
111-210/404 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
59338 |
Q9HB21 |
Cytoplasm, Cell membrane |
OTTHUMP00000020651; PH domain containing family A member 1; PH domain-containing family A member 1; PKHA1_HUMAN; Pleckstrin homology domain containing family A member 1; Pleckstrin homology domain containing, family A (phosphoinositide binding specific) member; Pleckstrin homology domain-containing family A member 1; PLEKHA1; Tandem PH domain containing protein 1; Tandem PH domain-containing protein 1; TAPP 1; TAPP-1; TAPP1. |
This gene encodes a pleckstrin homology domain-containing adapter protein. The encoded protein is localized to the plasma membrane where it specifically binds phosphatidylinositol 3,4-bisphosphate. This protein may be involved in the formation of signaling complexes in the plasma membrane. Polymorphisms in this gene are associated with age-related macular degeneration. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 5.[provided by RefSeq, Sep 2010] |
Application Dilution |
WB |
1:300-5000 |
IF(IHC-P) |
1:50-200 |
IF(IHC-F) |
1:50-200 |
IF(ICC) |
1:50-200 |