Overview |
bs-12613R-BF405 |
PELI3 Polyclonal Antibody, AbBy Fluor® 405 Conjugated |
WB, IF(IHC-P), IF(IHC-F), IF(ICC) |
Mouse |
Human, Rat, Dog, Cow, Sheep, Pig, Horse, Rabbit |
Specifications |
AbBy Fluor® 405 |
Rabbit |
KLH conjugated synthetic peptide derived from human PELI3 |
301-400/468 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
246330 |
Q8N2H9 |
Cytoplasm |
E3 ubiquitin-protein ligase pellino homolog 3; PELI3; Pellino-3; RING-type E3 ubiquitin transferase pellino homolog 3 |
E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates 'Lys-63'-linked polyubiquitination of IRAK1. Can activate AP1/JUN and ELK1. Not required for NF-kappa-B activation. |
Application Dilution |
WB |
1:300-5000 |
IF(IHC-P) |
1:50-200 |
IF(IHC-F) |
1:50-200 |
IF(ICC) |
1:50-200 |