mGluR5 Polyclonal Antibody

$Formalin-fixed and paraffin embedded rat brain labeled with Anti-GRM5\/mGluR5 Polyclonal Antibody, Unconjugated (bs-1244R) followed by conjugation to the secondary antibody and DAB staining$

Formalin-fixed and paraffin embedded rat brain labeled with Anti-GRM5\/mGluR5 Polyclonal Antibody, Unconjugated (bs-1244R) followed by conjugation to the secondary antibody and DAB staining

$Formalin-fixed and paraffin embedded rat brain labeled with Anti GRM5\/mGluR5 Polyclonal Antibody, Unconjugated (bs-1247R) at 1:200 followed by conjugation to the secondary antibody Goat Anti-Rabbit IgG, FITC conjugated (bs-0295G-FITC) used at 1:200 dilution for 40 minutes at 37\u00b0C and DAPI staining.$

Formalin-fixed and paraffin embedded rat brain labeled with Anti GRM5\/mGluR5 Polyclonal Antibody, Unconjugated (bs-1247R) at 1:200 followed by conjugation to the secondary antibody Goat Anti-Rabbit IgG, FITC conjugated (bs-0295G-FITC) used at 1:200 dilution for 40 minutes at 37\u00b0C and DAPI staining.

Applications

WB
ELISA
IHC-P
IHC-F
IF(IHC-P)
IF(IHC-F)
IF(ICC)

Reactivity

Predicted Reactivity

Human
Mouse
Dog
Sheep
Chicken

Overview
Catalog #	bs-1247R
Product Name	mGluR5 Polyclonal Antibody
Applications	WB, ELISA, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC)
Reactivity	Rat
Predicted Reactivity	Human, Mouse, Dog, Sheep, Chicken
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	KLH conjugated synthetic peptide derived from mouse GRM5
Immunogen Range	201-300/1204
Clonality	Polyclonal
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition	Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID	108071
Swiss Prot	Q3UVX5
Subcellular location	Cell membrane
Synonyms	Glu5R; Gprc1e; mGluR5; mGluR5b; AI850523; 6430542K11Rik; Metabotropic glutamate receptor 5; Grm5
Background	G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity (By similarity).
Application Dilution
WB	1:300-5000
ELISA	1:500-1000
IHC-P	1:200-400
IHC-F	1:100-500
IF(IHC-P)	1:50-200
IF(IHC-F)	1:50-200
IF(ICC)	1:50-200