CDKN2A/p19ARF Polyclonal Antibody

Overview
Catalog #	bs-1174R
Product Name	CDKN2A/p19ARF Polyclonal Antibody
Applications	ELISA, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC)
Reactivity	Rat
Predicted Reactivity	Mouse
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	KLH conjugated synthetic peptide derived from mouse CDKN2A/p19ARF
Immunogen Range	65-169/169
Clonality	Polyclonal
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition	Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID	12578
Swiss Prot	Q64364
Subcellular location	Nucleus
Synonyms	Arf; Alternative reading frame; smARF; p19ARF; p19; Cyclin-dependent kinase inhibitor 2A, isoforms 1/2; Cyclin-dependent kinase 4 inhibitor A; Tumor suppressor ARF; Cdkn2a
Background	Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein.
Application Dilution
ELISA	1:500-1000
IHC-P	1:200-400
IHC-F	1:100-500
IF(IHC-P)	1:50-200
IF(IHC-F)	1:50-200
IF(ICC)	1:50-200