Metabotropic glutamate receptor 2 Antibody

$Formalin-fixed and paraffin embedded rat brain tissue labeled with Anti-GRM2\/GLUR2 Polyclonal Antibody, Unconjugated (bs-1161R) at 1:300 followed by conjugation to the secondary antibody and DAB staining\\n$

Formalin-fixed and paraffin embedded rat brain tissue labeled with Anti-GRM2\/GLUR2 Polyclonal Antibody, Unconjugated (bs-1161R) at 1:300 followed by conjugation to the secondary antibody and DAB staining\\n

$Lane 1: Mouse Cerebrum tissue lysates; Lane 2: Mouse Cerebellum tissue lysates; Lane 3: Rat Cerebrum tissue lysates; Lane 4: Human SH-SY5Y cell lysates probed with GRM2 \/Metabotropic glutamate receptor 2 Polyclonal Antibody, Unconjugated (bs-1161R) at 1:1000 dilution and 4\u00b0C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.$

Lane 1: Mouse Cerebrum tissue lysates; Lane 2: Mouse Cerebellum tissue lysates; Lane 3: Rat Cerebrum tissue lysates; Lane 4: Human SH-SY5Y cell lysates probed with GRM2 \/Metabotropic glutamate receptor 2 Polyclonal Antibody, Unconjugated (bs-1161R) at 1:1000 dilution and 4\u00b0C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.

Applications

WB
ELISA
IHC-P
IHC-F
IF(IHC-P)
IF(IHC-F)
IF(ICC)
ICC

Reactivity

Predicted Reactivity

Human
Mouse
Cow
Horse
Chicken

Overview
Catalog #	bs-1161R
Product Name	Metabotropic glutamate receptor 2 Antibody
Applications	WB, ELISA, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC), ICC
Reactivity	Rat
Predicted Reactivity	Human, Mouse, Cow, Horse, Chicken
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	KLH conjugated synthetic peptide derived from human GRM2
Immunogen Range	801-872/872
Clonality	Polyclonal
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition	Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID	2912
Swiss Prot	Q14416
Subcellular location	Cell membrane
Synonyms	GLUR2; mGlu2; GPRC1B; MGLUR2; Metabotropic glutamate receptor 2; GRM2
Background	G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization.
Application Dilution
WB	1:300-5000
ELISA	1:500-1000
IHC-P	1:200-400
IHC-F	1:100-500
IF(IHC-P)	1:50-200
IF(IHC-F)	1:50-200
IF(ICC)	1:50-200
ICC	1:100-500