| Overview |
| bs-11568R-Cy3 |
| HS1BP3 Polyclonal Antibody, Cy3 Conjugated |
| IF(IHC-P), IF(IHC-F), IF(ICC) |
| Human |
| Mouse, Rat, Dog, Cow, Sheep, Pig, Horse, Rabbit |
| Specifications |
| Cy3 |
| Rabbit |
| KLH conjugated synthetic peptide derived from human HS1BP3 |
| 51-130/392 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| Cytoplasm |
| ETM2; FLJ14249; H1BP3_HUMAN; HCLS1 binding protein 3; HCLS1-binding protein 3; HS1 binding protein 3; HS1 BP3; HS1-BP3; HS1-binding protein 3; Hs1bp3; HSP1BP-3. |
| HS1BP3 is a 392 amino acid protein that contains one PX (phox homology) domain, a leucine zipper, immunoreceptor tyrosine-based inhibitory motif-like motifs and multiple proline-rich regions. Expressed primarily in brain, HS1BP3 is encoded by a gene mapping to human chromosome 2p24.1. The gene encoding HS1BP3 is frequently mutated in familial essential tremor, a disorder characterized by kinetic tremor the the hands, voice or head, though there is no correlation to Parkinson disease. HS1BP3 interacts with HAX-1?s SH3 domain, and may also play a role in the regulation of catecholamine and serotonin metabolism. Acting as a regulator of IL-2 signaling, HS1BP3 is likely involved in lymphocyte activation. |
| Application Dilution |
| IF(IHC-P) |
1:50-200 |
| IF(IHC-F) |
1:50-200 |
| IF(ICC) |
1:50-200 |
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