NPY4R Polyclonal Antibody, Biotin Conjugated
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-11522R-Biotin |
| Product Name | NPY4R Polyclonal Antibody, Biotin Conjugated |
| Applications | WB, ELISA, IHC-P, IHC-F |
| Reactivity | Mouse |
| Predicted Reactivity | Human, Rabbit |
| Specifications | |
| Conjugation | Biotin |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human NPY4R |
| Immunogen Range | 151-250/375 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Subcellular location | Cell membrane |
| Synonyms | Neuropeptide Y receptor type 4; Neuropeptide Y receptor Y4; NPY 4R; NPY R4; NPY Y4; NPY Y4 receptor; NPY-Y4 receptor; NPY4 R; NPY4-R; NPY4R; NPY4R_HUMAN; NPYR 4; NPYR4; NPYY 4; NPYY4; NPYY4-R; Y4 receptor. |
| Background | Pancreatic polypeptide (PP), neuropeptide Y (NPY), and peptide YY (PYY) are related 36-amino acid hormones. A number of structurally related receptors for these peptides have been isolated, NPY1-R, NPY2-R, NPY3-R, NPY4-R, NPY5-R, and NPY6-R. NPY4-R is expressed in several human tissues, including brain, coronary artery, and ileum. NPY4-R maps to human chromosome 10q11.2. NPY-5R, isolated from rat hypothalamus, encodes a 456-amino acid protein with less than 35% overall identity to known Y-type receptors. The human NPY5-R sequence is nearly identical to, but in the opposite orientation from, that of the human NPY1-R sequence. NPY5-R localizes to the paraventricular hypothalamic nucleus, the lateral hypothalamus, and other locations consistent with a role in the control of feeding behavior. The gene which encodes NPY5-R maps to human chromosome 4q32.2. NPY6-R is abundantly expressed in human heart and skeletal muscle and the gene which encodes NPY6-R maps to human chromosome 5q31. |
| Application Dilution | |
| WB | 1:300-5000 |
| ELISA | 1:500-1000 |
| IHC-P | 1:200-400 |
| IHC-F | 1:100-500 |
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