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NSE1 Polyclonal Antibody, AbBy Fluor® 594 Conjugated

Applications

  • WB
  • IF(IHC-P)
  • IF(IHC-F)
  • IF(ICC)

Reactivity

  • Rat
  • Others

Predicted Reactivity

  • Human
  • Mouse
  • Dog
  • Cow
  • Pig
  • Chicken
  • Zebrafish
Overview
Catalog # bs-11010r-bf594-100ul
Product Name NSE1 Polyclonal Antibody, AbBy Fluor® 594 Conjugated
Applications WB, IF(IHC-P), IF(IHC-F), IF(ICC)
Reactivity Rat, Others
Predicted Reactivity Human, Mouse, Dog, Cow, Pig, Chicken, Zebrafish
Specifications
Conjugation AbBy Fluor® 594
Host Rabbit
Source KLH conjugated synthetic peptide derived from human NSE1/FAM84A
Immunogen Range 151-250/292
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 3859
Synonyms FAM 84A; Family with sequence similarity 84 member A; family with sequence similarity 84, member A; FLJ35392; Neurologic sensory protein 1; Neurological/sensory 1; NSE 1; NSE1; PP11517; Protein FAM84A; Protein NSE1.
Background FAM84A is a 292 amino acid protein that belongs to the FAM84 family of proteins. Predominantly expressed in testis, FAM84A shares 44% amino acid identity with the related protein FAM84B. FAM84A localizes to a subcellular membrane region where there is no contact between neighboring cells and is believed to play a role in cell morphology and motility. More specifically, the expression of FAM84A increases cell motility. Two FAM84A isoforms are expressed due to alternative splicing events. Isoform 2 can be phosphorylated on various serine residues and this phosphorylation is associated with cellular morphology. FAM84A is upregulated in colorectal cancer, lung cancer, pancreatic cancer, cholangiocarcinoma and bladder cancer tissues. Via its ability to increase cell motility, FAM84A may contribute to the invasion and metastasis of cancer cells.
Application Dilution
WB 1:300-5000
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200