Overview |
bs-10757R-BF594 |
GPM6A Polyclonal Antibody, AbBy Fluor® 594 Conjugated |
WB, FCM, IF(IHC-P), IF(IHC-F), IF(ICC) |
Mouse, Rat |
Human, Dog, Rabbit |
Specifications |
AbBy Fluor® 594 |
Rabbit |
KLH conjugated synthetic peptide derived from human GPM6A |
151-250/278 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
2823 |
P51674 |
Cell membrane |
M6A; GPM6; Neuronal membrane glycoprotein M6-a; GPM6A |
Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor. |
Application Dilution |
WB |
1:300-5000 |
FCM |
1:20-100 |
IF(IHC-P) |
1:50-200 |
IF(IHC-F) |
1:50-200 |
IF(ICC) |
1:50-200 |