Overview |
bs-1035R-HRP |
CD86 Polyclonal Antibody, HRP Conjugated |
WB, ELISA, IHC-P, IHC-F |
Human, Mouse, Rat, Dog |
Cow, Sheep, Pig |
Specifications |
HRP |
Rabbit |
KLH conjugated synthetic peptide derived from rat CD86 |
140-175/313 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
56822 |
O35531 |
Cell membrane |
B7-2, Cd86 antigen; Cd86; Membrane glycoprotein |
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms. |
Application Dilution |
WB |
1:300-5000 |
ELISA |
1:500-1000 |
IHC-P |
1:200-400 |
IHC-F |
1:100-500 |