New to Bioss? Enjoy 35% of your first order. Use code "FirstOrder35" - Offer valid for new U.S. Customers on direct orders only

C5R1 Polyclonal Antibody, PE Conjugated

Applications

  • WB

Reactivity

  • Human

Predicted Reactivity

  • Rat
  • Dog
  • Cow
  • Sheep
  • Pig
  • Rabbit
  • Guinea Pig
Overview
Catalog # bs-10288r-pe-100ul
Product Name C5R1 Polyclonal Antibody, PE Conjugated
Applications WB
Reactivity Human
Predicted Reactivity Rat, Dog, Cow, Sheep, Pig, Rabbit, Guinea Pig
Specifications
Conjugation PE
Host Rabbit
Source KLH conjugated synthetic peptide derived from human C5R1
Immunogen Range 51-150/350
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 728
Swiss Prot P21730
Subcellular location Cell membrane
Synonyms C5A; C5AR; C5R1; CD88; C5a anaphylatoxin chemotactic receptor 1; C5a anaphylatoxin chemotactic receptor; C5a-R; C5AR1
Background Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events (PubMed:8182049, PubMed:7622471, PubMed:9553099). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production (PubMed:10636859, PubMed:15153520).
Application Dilution
WB 1:300-5000