| Overview |
| bs-0523r-bf350-100ul |
| SOX2 Polyclonal Antibody, AbBy Fluor® 350 Conjugated |
| WB, FCM, IF(IHC-P), IF(IHC-F), IF(ICC) |
| Human, Mouse, Rat, Goat |
| Dog, Cow, Sheep, Pig, Horse, Chicken, Rabbit |
| Specifications |
| AbBy Fluor® 350 |
| Rabbit |
| KLH conjugated synthetic peptide derived from mouse Transcription factor SOX-2 |
| 227-317/317 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 20674 |
| P48432 |
| Nucleus |
| lcc; ysb; Sox-2; Transcription factor SOX-2; Sox2 |
| Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP26. Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity). |
| Application Dilution |
| WB |
1:300-5000 |
| FCM |
1:20-100 |
| IF(IHC-P) |
1:50-200 |
| IF(IHC-F) |
1:50-200 |
| IF(ICC) |
1:50-200 |
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