BAIAP2 Polyclonal Antibody, HRP Conjugated

Applications

WB
ELISA
IHC-P
IHC-F

Reactivity

Human
Mouse
Rat

Overview
Catalog #	bs-0242R-HRP
Product Name	BAIAP2 Polyclonal Antibody, HRP Conjugated
Applications	WB, ELISA, IHC-P, IHC-F
Reactivity	Human, Mouse, Rat
Specifications
Conjugation	HRP
Host	Rabbit
Source	KLH conjugated synthetic peptide derived from human IRS P53
Immunogen Range	151-250/552
Clonality	Polyclonal
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition	Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID	10458
Subcellular location	Cytoplasm, Cell membrane
Synonyms	Insulin receptor substrate P53; IRSp53; IRS P53; IRS-P53; Baiap2; BAI1 associated protein 2 isoform 3; Brain-specic angiogenesis inhibitor 1-associated protein 2; BAI1-associated protein 2; Insulin receptor tyrosine kinase substrate protein p53; Insulin receptor substrate p53; Insulin receptor substrate protein of 53 kDa; IRSp53; BAIP2_HUMAN; BAI-associated protein 2; BAI1-associated protein 2; Protein BAP2; Fas ligand-associated factor 3; Insulin receptor substrate p53/p58; Insulin receptor substrate protein of 53 kDa; FLAF3; IRS-58; IRSp53/58.
Background	The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This interaction at the cytoplasmic membrane is crucial to the function of this protein, which may be involved in neuronal growth-cone guidance. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. Alternative splicing of the end of this gene results in three products of undetermined function.
Application Dilution
WB	1:300-5000
ELISA	1:500-1000
IHC-P	1:200-400
IHC-F	1:100-500

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