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Nogo-A Polyclonal Antibody, PE Conjugated

Applications

  • WB
  • FCM

Reactivity

  • Human
  • Rat

Predicted Reactivity

  • Mouse
Overview
Catalog # bs-0134R-PE
Product Name Nogo-A Polyclonal Antibody, PE Conjugated
Applications WB, FCM
Reactivity Human, Rat
Predicted Reactivity Mouse
Specifications
Conjugation PE
Host Rabbit
Source KLH conjugated synthetic peptide derived from mouse RTN4 protein
Immunogen Range 301-400/1192
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 68585
Swiss Prot Q99P72
Subcellular location Cytoplasm, Cell membrane
Synonyms ASY; NgA; NOGO; NSP-CL; Nogo-A; Nogo-B; Nogo-C; AA407876; AA409940; AA960376; mKIAA0886; mKIAA4153; 1110020G17Rik; C130026I10Rik; Reticulon-4; Neurite outgrowth inhibitor; Nogo protein; Rtn4; Kiaa0886
Background Developmental neurite growth regulatory factor with a role as a negative regulator of axon-axon adhesion and growth, and as a facilitator of neurite branching. Regulates neurite fasciculation, branching and extension in the developing nervous system. Involved in down-regulation of growth, stabilization of wiring and restriction of plasticity in the adult CNS. Regulates the radial migration of cortical neurons via an RTN4R-LINGO1 containing receptor complex. May inhibit BACE1 activity and amyloid precursor protein processing.
Application Dilution
WB 1:300-5000
FCM 1:20-100