Overview |
bs-0126R-PE-Cy7 |
HSP70 Polyclonal Antibody, PE-Cy7 Conjugated |
WB, FCM |
Human, Mouse, Rat, Chicken, Others |
Dog, Pig, Rabbit |
Specifications |
PE-Cy7 |
Rabbit |
KLH conjugated synthetic peptide derived from human HSP70 |
481-534/641 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
3303 |
P08107 |
Cytoplasm |
HSP72; HSPA1; HSP7I; HSP7-1; HSP7-1A; HEL-S-13; Heat shock 7 kDa protein 1A/1B; Heat shock 7 kDa protein 1/2; HSP7-1/HSP7-2; HSP7.1/HSP7.2; HSPA1A; HSX7 |
In cooperation with other chaperones, Hsp7s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection, serves as a post-attachment receptor for the virus to facilitate entry into the cell. |
Application Dilution |
WB |
1:300-5000 |
FCM |
1:20-100 |