Isohelenin

Overview
Catalog #	bs-83116c-5-mg
Product Name	Isohelenin
Specifications
Storage Buffer	White solid
Storage Condition	-20°C
Target
Product Information	A sesquiterpene lactone isolated from Mexican Indian medicinal plants known to have anti-inflammatory properties. A potent inhibitor of NFB (complete inhibition at 5 M)1 acting via inhibition of IKK6. Isohelenin-mediated NFB inhibition suppresses IL-8 expression2, iNOS expression3 and RANTES biosynthesis4. Displays protective effects in endotoxic shock in rodent models.5 Induces apoptosis in glioma cells.6
Description	CAS Number: 470-17-7 Chemical Name: (3aR,8aR,9aR)-8a-methyl-3,5-dimethylenedecahydronaphtho[2,3-b]furan-2(3H)-one Molecular weight: 232.32 Formula: C15H20O2 Solubility: DMSO (50 mg/ml) Ethanol (30 mg/ml) Physical Properties: White solid Purity: 98% by TLC NMR (Conforms)