GRL-0617

Overview
Catalog #	bs-83075c-5-mg
Product Name	GRL-0617
Specifications
Storage Buffer	Off-white solid
Storage Condition	-20°C
Target
Product Information	GRL-0617 is a potent (IC50 = 600 nM) noncovalent inhibitor of severe acute respiratory syndrome-coronavirus papain-like protease (SARS-CoV PLpro). GRL0617 inhibited SARS-CoV viral replication in Vero E6 cells with no cytotoxicity (EC50 = 15 µM). Inactive against human DUB-like proteases HAUSP, USP18, UCH-L1, UCH-L3, and PLP2.
Description	CAS Number: 1093070-16-6 Chemical Name: 5-Amino-2-methyl-N-(1R-naphthalen-1-yl-ethyl)benzamide Molecular weight: 304.39 Formula: C20H20N2O Solubility: DMSO (>30 mg/ml) Ethanol (>15 mg/ml) Physical Properties: Beige solid Purity: 99% by HPLC NMR (Conforms)