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pan Cytokeratin Polyclonal Antibody, AbBy Fluor® 594 Conjugated

Applications

  • IF(IHC-P)
  • IF(IHC-F)
  • IF(ICC)

Reactivity

  • Human
  • Rat

Predicted Reactivity

  • Mouse
Overview
Catalog # bs-5352R-BF594
Product Name pan Cytokeratin Polyclonal Antibody, AbBy Fluor® 594 Conjugated
Applications IF(IHC-P), IF(IHC-F), IF(ICC)
Specificity This will target: CK4; CK75; CK3; CK2; CK6C; CK6A; keratin 6E
Reactivity Human, Rat
Predicted Reactivity Mouse
Specifications
Conjugation AbBy Fluor® 594
Host Rabbit
Source KLH conjugated synthetic peptide derived from human CK5
Immunogen Range 331-430/590
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Subcellular location Cytoplasm
Synonyms CK4; CK75; CK3; CK2; CK6C; CK6A; keratin 6E; P-CK
Background Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinising tissue (ie., skin) and non keratinising cells (ie., mesothelial cells). Although not a traditional marker for endothelial cells, cytokeratins have also been found in some microvascular endothelial cells. At least 20 different cytokeratins (CK) in the molecular range of 40 to 70 kDa and isoelectric points of 5 to 8.5 can be identified using two dimensional gel electrophoresis. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells. Defects in KRT5 are a cause of epidermolysis bullosa simplex.
Application Dilution
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200