| Overview |
| bsm-70312M |
| Vimentin Antibody |
| WB, IHC, ICC |
| Specific for endogenous levels of the ~50 kDa vimentin protein. |
| Human, Mouse, Rat |
| Dog, Bovine, Sheep, Horse, Chicken, Cat, Rabbit, Guinea Pig, Goat, Zebrafish, Fish, Hamster, Drosophila, Xenopus, Non-Human Primate, Lizard, Vole, Finch |
| Specifications |
| Unconjugated |
| Mouse |
| Recombinant human vimentin purified from E. coli. |
| Monoclonal |
| 2D1 |
| IgG2a |
| Lot Dependent |
| Purified by Protein G. |
| PBS + 10 mM NaN3. |
| Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year. |
| Target |
| 7431 |
| P08670 |
| CTRCT30 antibody, Epididymis luminal protein 113 antibody, FLJ36605 antibody, HEL113 antibody, VIM antibody, VIME_HUMAN antibody, Vimentin antibody |
| Vimentin is the major protein subunit of the 10nm or intermediate filaments (IFs) found in many kinds of mesenchymal and epithelial cells as well as developing neuronal and astrocytic precursor cells in the CNS. Vimentin is thought to be critically involved in lymphocyte adhesion and transmigration (Nieminen M et al. 2006). Copolymers are frequently formed between vimentin and other IFs, such as GFAP (in many kinds of astrocytes), desmin (in muscle cells) and neurofilament proteins (in developing neurons). Antibodies to vimentin are useful in studies of stem cells and generally to reveal the filamentous cytoskeleton. Recent studies suggest that vimentin affects prostate cancer cells motility and invasiveness (Zhao et al. 2008). |
| Application Dilution |
| WB |
1:300-5000 |
| IHC |
|
| ICC |
1:100-500 |
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